我认为我申请的物质有门槛。如果RAC不同意我的评估怎么办？

我认为我申请的物质有门槛。如果RAC不同意我的评估怎么办？

I consider that the substance that I will apply for has a threshold. What if RAC disagrees with my assessment?

RAC 计划为已列入附件 XIV 的物质制定“参考 DNEL”和“参考剂量反应关系”。其目标是在最迟申请日期到期之前提供这些内容（参见问答 752）。如果您不同意 RAC 的观点，您可以在申请中说明理由。RAC 将在意见征询过程中对此进行评估。如果 RAC 未在最迟申请日期之前提供“参考 DNEL”或“参考剂量反应关系”，它将在意见征询过程中提供。无论如何，您和 RAC 都需要在意见征询过程中澄清与物质阈值相关的可能存在的科学问题。如果无法证明阈值，则无法根据第 60(2) 条关于充分控制的规定申请。但是，可以根据第 60(4) 条评估申请。在这种情况下，ECHA 强烈建议申请中包含社会经济分析（参见问答 617）。

RAC intends to develop "reference DNELs" and "reference dose response relationships" for substances that have been listed in Annex XIV. The intention is to make these available before the latest application date has expired (see Q&A 752).   If you disagree with RAC's view you can justify this in your application. RAC will evaluate this during the opinion making process.   If RAC has not made the "reference DNELs" or ""reference dose response relationships" available before the latest application date it will do so during the opinion making. In any case, you and RAC will need to clarify the possible scientific issues relating to the thresholdness of the substance during the opinion making process.   If a threshold cannot be demonstrated, it is not possible to apply based on Article 60(2) in relation to adequate control. However, the application can be evaluated based on Article 60(4). In this case ECHA strongly recommends that the application contains a socio-economic analysis(see Q&A 617).