如果络合剂和金属盐溶液中形成的金属络合物未经分离，是否需要注册？

如果络合剂和金属盐溶液中形成的金属络合物未经分离，是否需要注册？

Does a metal-complex, formed within a solution of a complexing agent and a metal salt, have to be registered if it is not isolated?

是的。只有满足以下所有条件，水溶液中的离子物质才可根据 REACH 附件 V 第 3 和第 4 条获得豁免：i) 水溶液中的所有起始物质（盐、酸和碱）均已注册；ii) 水溶液中的所有盐均未从溶液中分离出来；iii) 盐在溶液中保持离子形式。在本例中，第三个条件不成立，因为盐在复合物中不保持离子形式。因此，附件 V 的豁免不适用，复合物需要注册（参见附件 V 指南的附件 1“离子混合物”）。由螯合离子组成的复合物如果本身制造、进口或投放市场，则必须注册。然而，可以考虑附件五中不同豁免的适用性，例如，如果复合物是由螯合剂按预期功能产生的（即“物质本身不是制造、进口或投放市场的，而是由以下情况下发生的化学反应产生的：（a）[...]螯合剂[...]按预期功能产生”）。

Yes. Ionic substances in an aqueous solution are exempted from registration under Annex V entries 3 & 4 to REACH only if all of the following conditions are fulfilled: i) All starting substances (salts, acids and bases) of the aqueous solution are registered; and ii) None of the salts in the aqueous solution is isolated from the solution; and iii) The salts remain in their ionic form in the solution.In this particular case, the third condition is not fulfilled, since the salts do not remain in their ionic form in the complex. Therefore, the Annex V exemption does not apply, and the complex would be subject to registration (see Attachment 1 ‘Ionic Mixtures' of the Guidance for Annex V).Complexes consisting of chelated ions must be registered if they are themselves manufactured, imported or placed on the market. However, the applicability of different exemptions in Annex V could be considered, e.g., if the complex results from a chelating agent functioning as intended (i.e., ‘substances which are not themselves manufactured, imported or placed on the market and which result from a chemical reaction that occurs when: (a) a [...] chelating agent [...] functions as intended').