除了注册档案中的数据外，ECHA 还使用哪些信息来源？

除了注册档案中的数据外，ECHA 还使用哪些信息来源？

Which sources of information is ECHA using in addition to the data in the registration dossiers?

通用筛选算法的主要输入来自 REACH 注册档案。关于提交的数据，通用筛选算法也使用 C&L 清单中的数据，但通常更重视以注册档案中的测试数据为基础的分类。除了 REACH 档案和 C&L 通知中提交的数据外，算法还使用外部工具和数据库，根据化学名称和数字标识符（例如 CAS 编号和 EC 编号）推导出分子结构。这些结构用于通过模型预测其命运和（生态）毒理学特性。最后，算法还使用外部清单，例如 SIN 清单 (http://chemsec.org/what-we-do/sin-list)，以及其他监管机制的评估，例如澳大利亚的 IMAP 计划 (http://www.nicnas.gov.au/chemical-information/imap-assessments/imap-assessments)。如果筛选物质与训练集中的某种测试物质相同或相似，ECHA 也会使用用于 QSAR 模型开发的数据集。不同的信息来源及其使用方式在每年更新的定义文件中进行了描述：https://echa.europa.eu/screening。

The primary input to the common screening algorithms come from REACH registration dossiers. With regard to submitted data, common screening also uses the data in the C&L inventory, although more weight is usually given to classifications that are underpinned by test data in the registration dossiers. In addition to the submitted data in REACH dossiers and C&L notifications, the algorithms use external tools and databases to derive molecular structures from the chemical names and numerical identifiers, such as the CAS number and the EC number. These structures are used to run predictions for fate and (eco)toxicological properties using models. Finally, the algorithms use external lists, such as the SIN list: (http://chemsec.org/what-we-do/sin-list), and the assessments from other regulatory regimes, such as the IMAP programme: (http://www.nicnas.gov.au/chemical-information/imap-assessments/imap-assessments) in Australia. ECHA is also using datasets used for QSAR model development in case the screened substance is identical or similar to one of the tested substances in the training sets. The different sources of information and how these are used are described in the definition document that is updated annually at: https://echa.europa.eu/screening.